The effect of increase in quantity of tricyclic antidepressant for non acute zoster-associated pain (more than 30 days after the onset of herpes zoster)

DOI Web Site 1 Citations 13 References
  • HIRATA Kazuhiko
    Department of Anesthesiology, Fukuoka University Faculty of Medicine Department of Anesthesiology, Fukuoka University Faculty of Medicine
  • HIGA Kazuo
    Department of Anesthesiology, Fukuoka University Faculty of Medicine Department of Anesthesiology, Fukuoka University Faculty of Medicine
  • HIROTA Kazunori
    Department of Anesthesiology, Fukuoka University Faculty of Medicine Department of Anesthesiology, Fukuoka University Faculty of Medicine
  • IWASHITA Kouhei
    Department of Anesthesiology, Fukuoka University Faculty of Medicine Department of Anesthesiology, Fukuoka University Faculty of Medicine
  • SAKIMURA Keiko
    Department of Anesthesiology, Fukuoka University Faculty of Medicine Department of Anesthesiology, Fukuoka University Faculty of Medicine
  • IKEDA Mayumi
    Department of Anesthesiology, National Hospital Organization Kyushu Cancer Center Department of Anesthesiology, National Hospital Organization Kyushu Cancer Center
  • KENMIZAKI Yutaka
    Department of Anesthesiology, Karatsu Red Cross Hospital Department of Anesthesiology, Karatsu Red Cross Hospital
  • SHIBATA Shiho
    Department of Anesthesiology, Fukuoka University Faculty of Medicine Department of Anesthesiology, Fukuoka University Faculty of Medicine

Bibliographic Information

Other Title
  • 非急性帯状疱疹患者（皮疹発症30日以上の帯状疱疹患者）への三環系抗うつ薬増量の効果
  • ヒキュウセイ タイジョウホウシンカンジャ(ヒシンハッショウ 30ニチ イジョウ ノ タイジョウホウシンカンジャ)ヘ ノ サンカンケイ アラガウツ クスリ ゾウリョウ ノ コウカ

Search this article

Description

We retrospectively studied doses of tricyclic antidepressants (TCAs) for the treatment of non acute zoster-associated pain (more than 30 days after the onset of herpes zoster [ZAP]) in 58 patients who visited our department. TCAs had been taken in 26% of the patients, and anticonvulsants in 5%. We prescribed TCA, either amitriptyline or nortriptyline, to 88% of the patients, and anticonvulsants, either gabapentin or valproic acid, to 58%. Initial median daily dose of amitriptyline was 10.0 mg, which after 4 weeks was gradually increased to 50.0 mg (quartile range 22.5-93.8 mg). Mean pain decreased from 66.5 mm to 23.2 mm on a 100-mm visual analog scale (VAS). The initial median daily dose of nortriptyline was 10.0 mg, which after 4 weeks was gradually increased to 30.0 mg (21.5-50.0 mg). Pain decreased from 60.6 mm to 27.9 mm on VAS after 4 weeks. TCAs reduced non acute ZAP. The doses of TCA to control non-acute ZAP varied from patient to patient greatly.

Journal

Citations (1)*help

See more

References(13)*help

See more

Keywords

Details 詳細情報について

Report a problem

Back to top