Inhibitory Effect of Oligomeric Polyphenols from Peanut-skin on Sugar Digestion Enzymes and Glucose Transport
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- Tamura Tomoko
- Department of Nutritional Science, Faculty of Applied Bioscience, Tokyo University of Agriculture
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- Ozawa Megumi
- Advantec.co.,ltd
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- Kobayashi Shoko
- Research Center for Food Safety, Graduate School of Agricultural and Life Sciences, The University of Tokyo
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- Watanabe Hirohito
- Department of Life Science and Department of Agricultural Chemistry, Meiji University
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- Arai Soichi
- Department of Nutritional Science, Faculty of Applied Bioscience, Tokyo University of Agriculture
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- Mura Kiyoshi
- Department of Nutritional Science, Faculty of Applied Bioscience, Tokyo University of Agriculture
Description
Inhibitory effects of oligomeric polyphenols extracted from peanut skin on α-amylase, maltase, sucrase and glucose transport were investigated. Epicatechin-(4β→6)-epicatechin-(2β→O→7, 4β→8)-catechin (EEC) as a procyanidin trimer inhibited α-amylase activity in a dose-dependent manner, while (+)-catechin and procyanidin A1 as a procyanidin dimer did not show any inhibitory activity up to 5 mg/mL. In the case of sucrase, EEC showed inhibitory activity stronger than (+)-catechin and procyanidin A1. Inhibitory effects of peanut skin on glucose transport in the small intestine were also investigated. The level of glucose transport in Caco-2 cells was significantly decreased by EEC compared to (+)-catechin. These results suggest that the inhibitory effects of procyanidins on α-amylase and α-glucosidase, and the suppression of intestinal glucose transport may change with the degree of polymerization.
Journal
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- Food Science and Technology Research
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Food Science and Technology Research 21 (1), 111-115, 2015
Japanese Society for Food Science and Technology
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Details 詳細情報について
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- CRID
- 1390282679435387008
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- NII Article ID
- 130005061941
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- ISSN
- 18813984
- 13446606
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- Text Lang
- en
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- Data Source
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- JaLC
- Crossref
- CiNii Articles
- KAKEN
- OpenAIRE
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- Abstract License Flag
- Disallowed