Expression of HSP in Dental Root Pulp Cells due to Experimental Orthodontic Mechanical Stress

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  • Nakano Keisuke
    Hard Tissue Pathology Unit, Matsumoto Dental University Graduate School of Oral Medicine
  • Muraoka Rina
    Hard Tissue Pathology Unit, Matsumoto Dental University Graduate School of Oral Medicine
  • Tomida Mihoko
    Department of Oral Physiology, Matsumoto Dental University School of Dentistry
  • Matsuura Sachiko
    Department of Biology, Matsumoto Dental University School of Dentistry
  • Okafuji Norimasa
    Clinical Evaluation Unit, Matsumoto Dental University Graduate School of Oral Medicine
  • Chong Huat Siar
    Department of Oral Pathology, Oral Medicine & Periodontology, Faculty of Dentistry, University of Malaya
  • Kawakami Toshiyuki
    Hard Tissue Pathology Unit, Matsumoto Dental University Graduate School of Oral Medicine

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Using immunohistochemical techniques, we examined the expression of heat shock protein (HSP) appearing in murine dental pulp cells after the application of experimental orthodontic mechanical stress. We used Waldo's method, and the results demonstrate that the dental root pulp cells expressed HSP in a comparatively short time after stress. The results suggest that HSP works as one of the mechanisms to maintain homeostasis.

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