A case of herpes zoster associated with low-dose methotrexate for rheumatoid arthritis

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  • IMAMACHI Noritaka
    Department of Anesthesia, Hamada National Hospital Department of Anesthesiology, Shimane University School of Medicine
  • DOI Katsushi
    Department of Anesthesiology, Shimane University School of Medicine
  • SAITO Yoji
    Department of Anesthesiology, Shimane University School of Medicine

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  • 関節リウマチ患者に対する低用量メトトレキサート療法開始後に発症した帯状疱疹の1症例
  • カンセツ リウマチ カンジャ ニ タイスル テイヨウリョウ メトトレキサート リョウホウ カイシ ゴ ニ ハッショウ シタ タイジョウホウシン ノ 1 ショウレイ

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Abstract

A 60-year-old man had herpes zoster on the left upper limbs during treatment with low-dose methotrexate (MTX) for rheumatoid arthritis (RA). He felt pain in the left upper limbs in the daytime the day after starting low-dose MTX therapy. Skin eruption appeared in the pain area in the evening. Intravenous aciclovir and continuous epidural block were started. His pain decreased to VAS values of 0mm.<br>MTX therapy so metimes causes immunosuppression, with may become critical when patients have herpes zoster. Therefore, aciclovir should be administered as early as possible in the case of herpes zoster with RA treated with low-dose MTX.

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