Development of SPR Immunosensing System Using Microchannel Cell for Simultaneous Detection of Several Endocrine-Disrupting Chemicals
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- Miura Norio
- Advanced Science and Technology Center for Cooperative Research, Kyushu University
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- K. Vengatajalabathy Gobi
- Advanced Science and Technology Center for Cooperative Research, Kyushu University
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- Shoyama Yukihiro
- Graduate School of Pharmaceutical Sciences, Kyushu University
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- Maeda Hideaki
- Micro-space Chemistry Laboratory, AIST
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- Kawazumi Hirofumi
- Kinki University, Kyushu
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- Iwasaka Hiroyuki
- Omron Corporation, Electric Components Company, Nagaoka Lab., R&D Center
Bibliographic Information
- Other Title
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- SPR免疫センサとマイクロチャネルセルを用いた環境ホルモン類の多成分同時検出システムの開発
- SPR メンエキ センサ ト マイクロチャネルセル オ モチイタ カンキョウ ホルモンルイ ノ タセイブン ドウジ ケンシュツ システム ノ カイハツ
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Abstract
The endocrine-disrupting chemicals affect the functioning of hormones of animals and are called “environmental hormones". They exist in various environments at very low concentrations in the range of ppt to ppb levels. Thus, highly sensitive determination of environmental hormones with high selectivity is indispensable in regulating the ecosystem, and the instrumentation that allows the on-site analysis of environmental hormones is paid much attention. In this research project, we are aiming at development of new optical immunosensing system for highly sensitive, selective, on-site and simultaneous detection of several environmental hormones at low cost. We report here the results of our research investigations on application of immunosensing technique to highly sensitive detection of environmental hormones, preparation of monoclonal antibodies, fabrication of the microchannel, miniaturization of the surface-plasmon-resonance detector, design of the compact total-sensing-system.
Journal
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- IEEJ Transactions on Sensors and Micromachines
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IEEJ Transactions on Sensors and Micromachines 123 (7), 217-223, 2003
The Institute of Electrical Engineers of Japan
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Details 詳細情報について
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- CRID
- 1390282679436954880
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- NII Article ID
- 10011205866
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- NII Book ID
- AN1052634X
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- ISSN
- 13475525
- 13418939
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- NDL BIB ID
- 6633425
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed