書誌事項
- タイトル別名
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- QCM Sensor Using Membrane Proteins of Cell-derived Liposomes
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This paper presents a novel QCM (quartz crystal microbalance) sensor for detecting interactions between membrane proteins and their ligands using liposomes derived from human cells. First, liposomes having BCR (B-cell receptor) were derived directly from cell membranes by stimulating human lymphocyte cells, Ramos, with NaB (sodium butyrate). Next, the liposomes were separated from the cells by filtration and micronized by sonication. Then, the liposomes were immobilized on the surface of a QCM sensor chip using cell-anchoring molecules. Several experiments demonstrated that ligand detection is achieved by frequency reduction with application of the antibody against BCR.
収録刊行物
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- 電気学会論文誌E(センサ・マイクロマシン部門誌)
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電気学会論文誌E(センサ・マイクロマシン部門誌) 133 (5), 155-156, 2013
一般社団法人 電気学会
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詳細情報
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- CRID
- 1390282679437790464
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- NII論文ID
- 10031167011
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- NII書誌ID
- AN1052634X
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- ISSN
- 13475525
- 13418939
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
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- CiNii Articles
- KAKEN
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- 抄録ライセンスフラグ
- 使用不可