Inhibitory effects of thymoquinone from Nigella sativa on pathogenic Saprolegnia in fish.

DOI 6 Citations 21 References
  • HUSSEIN MORTADA M.A.
    Division of Fish Diseases, Nippon Veterinary and Animal Science University Department of Fish Diseases and Management, Faculty of Veterinary Medicine, Cairo University
  • EL-FEKI MOUSTAFA A.
    Division of Fish Diseases, Nippon Veterinary and Animal Science University Department of Zoology, Faculty of Science, El-Minia University
  • HATAI KISHIO
    Division of Fish Diseases, Nippon Veterinary and Animal Science University
  • YAMAMOTO ATSUSHI
    Oshino Trout Hatchery, Yamanashi Prefectural Fisheries Technology Center

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Description

he antimycotic activities of thymoquinone against some species of Saprolegnia pathogenic to fish as well as its toxic effect on selected farm fishes were investigated. Two Saprolegnia species pathogenic to fish, S. parasitica NJM 8604 and S. salmonis NJM 9851, were used. The minimum inhibitory concentrations (MICs) of thymoquinone against Saprolegnia parasitica and S. salmonis were 150 and 125 μg/ml, respectively, while the fungicidal effects on both strains were seen at 160 μg/ml. Tested zoospores of both Saprolegnia strains could not germinate after being exposed to 4 μg/ml of thymoquinone for 30 min. Thymoquinone was toxic to salmonids but less toxic to cyprinids.

Journal

  • Biocontrol Science

    Biocontrol Science 7 (1), 31-35, 2002

    The Society for Antibacterial and Antifungal Agents, Japan

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Keywords

Details 詳細情報について

  • CRID
    1390282679441036544
  • NII Article ID
    10011104968
  • NII Book ID
    AA11169621
  • DOI
    10.4265/bio.7.31
  • ISSN
    18840205
    13424815
  • Text Lang
    en
  • Data Source
    • JaLC
    • Crossref
    • CiNii Articles
  • Abstract License Flag
    Disallowed

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