Antibacterial Activity and Characteristics of Modified Ferrite Powder Coated with a Gemini Pyridinium Salt Molecule
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- SHIRAI AKIHIRO
- Department of Biological Science and Technology, Faculty of Engineering, The University of Tokushima
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- MAEDA TAKUYA
- Department of Biological Science and Technology, Faculty of Engineering, The University of Tokushima
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- OHKITA MOTOAKI
- Department of Biological Science and Technology, Faculty of Engineering, The University of Tokushima
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- NAGAMUNE HIDEAKI
- Department of Biological Science and Technology, Faculty of Engineering, The University of Tokushima
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- KOURAI HIROKI
- Department of Biological Science and Technology, Faculty of Engineering, The University of Tokushima
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This report describes the synthesis of an antibacterial material consisting of a gemini quaternary ammonium salt (gemini-QUAT) immobilized on ferrite powder, and its antibacterial activity. A gemini-QUAT containing two pyridinium residues per molecule, 4, 4'-[1, 3-(2, 2-dihydroxylmethy1-1, 3-dithiapropane)] bis (1-octylpyridinium bromide), was immobilized on ferrite powder by a reaction between the hydroxyl group of the QUAT and trimethoxysilane. Immobilization of the gemini-QUAT on ferrite (F-gemini-QUAT) was confirmed when the dye, bromophenol blue, was released from F-gemini-QUAT-dye after contact between ferrite and the dye. Elemental analysis of the QUAT-ferrite determined the molar amount of QUAT on the ferrite. The antibacterial effect of the ferrite was investigated using a batch treatment system, and this effect was compared with that of another QUAT-ferrite (F-mono-QUAT) binding a mono-QUAT, which possesses one pyridinium residue, prepared by the same immobilization method as F-gemini-QUAT. Results indicated the F-gemini QUAT possessed a higher bactericidal potency and broader antibacterial spectrum compared to F-mono-QUAT. In addition, this study suggested that gemini-QUATs possessed high bactericidal potency without being influenced by immobilization to materials, and the antibacterial activity and characteristics of Fgemini-QUAT could be attributed to the unique structure of the immobilized gemini-QUAT.
収録刊行物
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- Ｂｉｏｃｏｎｔｒｏｌ Ｓｃｉｅｎｃｅ
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Ｂｉｏｃｏｎｔｒｏｌ Ｓｃｉｅｎｃｅ 12 (3), 83-91, 2007
日本防菌防黴学会
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詳細情報 詳細情報について
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- CRID
- 1390282679441345152
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- NII論文ID
- 10019858615
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- NII書誌ID
- AA11169621
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- COI
- 1:CAS:528:DC%2BD2sXhtFGmsr3O
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- ISSN
- 18840205
- 13424815
- http://id.crossref.org/issn/13424815
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可