Synthesis of 4,4'-(Tetramethylenedicarbonyldiamino)hai-bis(1-decylpyridinium bromide) and Its Antimicrobial and Deodorant Characteristics.

DOI 被引用文献6件 参考文献13件 オープンアクセス

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A new bis-quaternary ammonium compound (bis-QAC), 4, 4'-(tetramethylenedicarbonyldiamino) bis (1-decylpyridinium bromide) (D-136) was synthesized, and its antimicrobial and deodorant characteristics were studied. A vinyl chloride polymer sheet containing D-136 (D-136 sheet) was prepared for practical use because D-136 exhibited a wide and effective antimicrobial spectrum of activity against both bacteria and fungi. The antibacterial and antifungal efficiency of the D-136 sheet was estimated according to the film covering method and the test for fungus resistance. Results showed that the growth of both bacteria and fungi was inhibited on the D-136 sheet. Furthermore, a model test for the deodorant efficiency of water-absorbing resins (SAP) containing D-136 (D-136 SAP) was done on the assumption that it might be applied for use in disposable diapers. To prevent the offensive odor arising from excreted urine in disposable diapers, it is necessary to inhibit the propagation of ureahydrolyzing bacteria in the water-absorbing layer. The microbe used for the experiment was Proteus mirabilis IFO 3849 which produces an enzyme (urease) capable of degrading urea and other compounds present in human urine to ammonia, methylamine and the like. As for the result of the model test, the generation of ammonia from human urine was inhibited on D-136 SAP.

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