肺癌におけるDNA ploidy解析の意義

  • 田川 泰
    長崎大学大学院医歯薬総合研究科保健学専攻
  • 西中 暁
    長崎大学大学院医歯薬総合研究科保健学専攻
  • 益子 洋一
    長崎大学医学部保健学科作業療法専攻

書誌事項

タイトル別名
  • Significance for Analysis of DNA Ploidy in Lung Carcinomas
  • -過去の結果より今後の活用を考える-
  • -It gropes for the future use referring to the past result-

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説明

<p>Many previous studies attempted to associate DNA ploidy with prognosis and malignant behavior for lung carcinomas as well as other carcinomas, but recently, the reports which are related to cellular DNA quantification in lung carcinomas decreased much more than before. Why did researchers stop having interest in the study of DNA ploidy? First of all, authors mentioned an outline of the history of DNA ploidy in lung carcinomas. We were anguished about many problems of DNA ploidy, and a difficult question was solved with patience. When it looks back on the history, authors found out that the analysis of DNA index is interesting in the malignant behavior of lung carcinomas which a distant metastasis (lung, brain, bone, et al) is high frequency. Furthermore, an questionable fact of DNA ploidy may be solved when DNA ploidy is combined with FISH and CGH methods. The authors emphasizes that interesting research is still left in the study of cellular DN Acontent.</p>

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詳細情報 詳細情報について

  • CRID
    1390282679449577600
  • NII論文ID
    130006832451
  • DOI
    10.18947/cytometryresearch.19.1_11
  • ISSN
    24240664
    09166920
  • 本文言語コード
    ja
  • データソース種別
    • JaLC
    • CiNii Articles
  • 抄録ライセンスフラグ
    使用不可

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