書誌事項
- タイトル別名
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- Experimental Study of Interstitial Photodynamic Therapy to Improve Therapeutic Value
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The purpose of this study was to evaluate interstitial photodynamic therapy using the Microselectron ® Flexible implant tube (Nucletron B. V.) for advanced cancer. VX2 carcinoma was transplanted subcutaneously into the femur of Japanese white rabbits. When the cancer grew to the size of 60 mm, a dose of 10 mg/kg of porfimer sodium (Photofrin ®, Wyeth Lederle Japan Ltd.) was administered intravenously. Microselectron ® tubes were implanted into the tumor at intervals of 20mm in which the optic fiber was inserted. Then irradiation was performed under conditions of 4mJoul/pulse and a pulse repetition frequency of 80Hz. The total light dose along a tube was 100Joul/cm. At 5 days after irradiation, the tumors had flatted, due to necrotic change. We suggest that interstitial photodynamic therapy using the Microselectron ® tube is applicable for treatment of solid oral cancer.
収録刊行物
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- 日本レーザー歯学会誌
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日本レーザー歯学会誌 12 (2), 92-96, 2001
日本レーザー歯学会
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詳細情報
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- CRID
- 1390282679452046208
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- NII論文ID
- 130003925086
- 80012651238
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- ISSN
- 21856702
- 09177450
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可