Plantago Ovata Consumption and Colorectal Mortality in Spain, 1995-2000

  • López José Carlos
    Department of Preventive Medicine and Public Health and History of Science, Faculty of Medicine, Complutense University
  • Villanueva Rosa
    Department of Preventive Medicine and Public Health and History of Science, Faculty of Medicine, Complutense University
  • Martínez-Hernández David
    Department of Preventive Medicine and Public Health and History of Science, Faculty of Medicine, Complutense University
  • Albaladejo Romana
    Department of Preventive Medicine and Public Health and History of Science, Faculty of Medicine, Complutense University
  • Regidor Enrique
    Department of Preventive Medicine and Public Health and History of Science, Faculty of Medicine, Complutense University
  • Calle María Elisa
    Department of Preventive Medicine and Public Health and History of Science, Faculty of Medicine, Complutense University

書誌事項

公開日
2009
資源種別
journal article
DOI
  • 10.2188/jea.je20080059
公開者
日本疫学会

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説明

Background: Consumption of Plantago ovata may protect against colorectal cancer. To test this hypothesis, an ecological study was performed to determine mortality rates and distribution of colorectal cancer, and the consumption and distribution of P ovata, in different provinces in Spain. The putative association between P ovata consumption and mortality from colorectal cancer was then evaluated.<BR>Methods: We conducted a comparative ecological study of Spanish provinces, with colorectal cancer mortality as the dependent variable and per capita consumption of P ovata by province and year as the independent variable. Associations were analyzed by calculating Spearman’s correlation coefficients and a Poisson multiple regression model.<BR>Results: Consumption of P ovata tended to be inversely correlated with mortality from colorectal cancer. In the Poisson regression analysis this tendency remained and reached statistical significance for the top quintile of P ovata consumption in the adjusted analysis (P = 0.042).<BR>Conclusions: Our results show an inverse trend between the consumption of P ovata and colorectal cancer mortality. We recommend additional observational studies of individuals, in order to better control confounding factors.

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