ALLERGIC AND NUTRITIONAL EVALUATION OF A DRINK WITH SOY PROTEIN HYDROLYSATE IN FOOD ALLERGIC CHILDREN

DOI 12 References Open Access
  • Iwasaki Eisaku
    Department of Pediatrics, Doai Memorial Hospital
  • Baba Minoru
    Department of Pediatrics, Doai Memorial Hospital
  • Kaminogawa Shuichi
    Department of Agricultural Chemistry, Faculty of Agriculture, The University of Tokyo
  • Enomoto Atsushi
    Department of Biological and Chemical Engineering, Faculty of Engineering, Gunma University
  • Totuka Mamoru
    Department of Agricultural Chemistry, Faculty of Agriculture, The University of Tokyo
  • Konishi Nawo
    Department of Agricultural Chemistry, Faculty of Agriculture, The University of Tokyo
  • Kimoto Minoru
    New Business Department, Food Research Institute, Fuji Oil Co., Ltd.

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  • 食物アレルギー小児に対する大豆ペプチド飲料のアレルギー学的, 栄養学的評価

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Nutritional availability of a drink with soy protein hydrolysate (Hinute D3; Fuji Oil Co., Ltd) was evaluated in 10 food allergic children. The soy peptide has 5.2 amino acids in average peptide length and contain 1.0% free amino acids. Binding ability of the soy hydrolysate to soy specific IgE antibodies of patient's sera was significantly lowered when compared with unhydrolysed soy protein (p<0.001).<br>Eight patients among 10 could take continuously the soy peptide drink over 3 months, but 2 patients experienced skin eruption and itching by the challenge tests of the soy peptide drink. During the period taking a can (6g protein in 200g) every day, hemoglobin, serum total protein and albumin for nutritional index were significantly improved, and body weight and height also increased favorably. Throughout feeding period, the soy peptide drink did not bring about aggravation of allergic symptoms or adverse reactions, and laboratory findings including blood and urine examinations were also in good order. Moreover, patients and their parents put value on taste of the soy peptide drink.<br>These results indicated that the soy peptide was useful in nutritional management of some part of food allergic children.

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