The Effect of Emu Oil on Lipid Metabolism in Rats

DOI 11 References
  • KATO Yuma
    Tokyo University of Agriculture, Faculty of Bio-Industry, Department of Food and Cosmetic Science, Laboratory of Aroma chemistry
  • MYODA Takao
    Tokyo University of Agriculture, Faculty of Bio-Industry, Department of Food and Cosmetic Science, Laboratory of Aroma chemistry
  • FUJIMORI Takane
    Tokyo University of Agriculture, Faculty of Bio-Industry, Department of Food and Cosmetic Science, Laboratory of Aroma chemistry
  • TOEDA Kazuki
    Tokyo University of Agriculture, Faculty of Bio-Industry, Department of Food and Cosmetic Science, Laboratory of Aroma chemistry
  • NISHIZAWA Makoto
    Tokyo University of Agriculture, Faculty of Bio-Industry, Department of Food and Cosmetic Science, Laboratory of Aroma chemistry
  • SAKURAI Tomonobu
    Tokyo University of Agriculture, Faculty of Bio-Industry, Laboratory of Health Science

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Other Title
  • エミューオイル投与がラットの脂質代謝に及ぼす影響

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Abstract

Unsaturated fatty acids such as oleic acid and linoleic acid are known to play important roles not only in physiological homeostasis as essential fatty acids but also suppressive effects on serum cholesterol level. Emu is a large ratite native in Australia, and emu oil prepared from subcutaneous adipose had been a universal medicine for native people in Australia. Emu oil is known to be rich in unsaturated fatty acids, such as oleic acid, and it was reported that oral administration of emu oil exhibited anti-inflammatory effect for dermatitis and arthritis. On the other hand, suppressive effects on serum lipid level and improvement of lipid metabolism were suggested, but precise data has not yet been reported. In this paper, we report the effects of oral administration of emu oil on lipid metabolism of rat. There was no significant difference in body weight and epididymis fat weight by 6 weeks administration of emu oil (1.0 mg/kg/ day). However, lipolytic response of the adipose cells isolated from epididymis fat stimulated by isoproterenol, was enhanced in the group administrated emu oil, compared with those of the group administrated lard or soy-bean oil. Our result indicated that oral administration of emu oil affected lipid metabolism of rat, and enhanced lipolytic response dose dependently. The effects of emu oil on lipid are notable functions for physiological homeostasis, and must be applied for functional foods and medicines.

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