Chemical Injury of the Oral Cavity in a Patient with Total Blindness and Granulomatosis with Polyangitis:A Case Report

  • KANO Keita
    Department of Dentistry and Oral Surgery, Uji Takeda Hospital Department of Dental Medicine, Kyoto Prefectural University of Medicine Graduate School of Medical Science
  • MURAYAMA Takafumi
    Department of Dentistry and Oral Surgery, Uji Takeda Hospital
  • SHIRASUGI Michihiro
    Department of Dental Medicine, Kyoto Prefectural University of Medicine Graduate School of Medical Science
  • YAMAMOTO Toshiro
    Department of Dental Medicine, Kyoto Prefectural University of Medicine Graduate School of Medical Science
  • KANAMURA Narisato
    Department of Dental Medicine, Kyoto Prefectural University of Medicine Graduate School of Medical Science
  • AKIYAMA Shigehisa
    Division of Special Care Dentistry, Osaka University Dental Hospital
  • MORISAKI Ichijiro
    Division of Special Care Dentistry, Osaka University Dental Hospital Department of Oral Health Science, Baika Women’s University

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Other Title
  • 多発血管炎性肉芽腫症起因の全盲患者に生じた口腔化学熱傷例

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<p>Chemical injuries to the oral cavity are relatively rare, usually caused by accidental ingestion in children, elderly, and dementia patients. Granulomatosis with polyangitis (GPA) is a rare disease of uncertain cause. GPA is characterized by necrotizing granulomatous inflammation of the respiratory tract, kidney, and other organs. Here, we report a case of chemical injury of the oral cavity in a patient with total blindness and GPA. A 78-year-old female was referred to our department because of pain of the oral cavity. She had torn open a small pack of calcium oxide desiccant for some rice crackers and accidentally ingested the desiccant. Oral examination revealed mild swelling at the right lower lip and erosion of the right buccal mucosa, tongue and oral floor. A gastrointestinal endoscopic examination showed no ulcer in the upper gastrointestinal tract. She was instructed to gargle with azulen sodium sulfonate and antibiotics were administered. After 7 days, the lesions healed successfully and she was discharged from the hospital.</p>

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