Effect of endotoxin on the lethal toxicity of various environmental pollutants for killifish (Oryzias latipes)

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  • 各種環境汚染物質のヒメダカ（Ｏｒｙｚｉａｓ　ｌａｔｉｐｅｓ）に対する致死毒性に及ぼす細菌内毒素の影響

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Abstract

Lethal toxicity of endotoxin was observed on killifish (Oryzias latipes) at relatively high temperature (30°C). Effect of endotoxin on the lethal toxicity of various pollutants was examined for killifish at 30°C. Permissible volumes of various dissolvents with and without endotoxin were determined at 30°C. Ten percent diethylether-dimethysulfoxide solution was chosen as a suitable dissolvent for water-insoluble pollutants with and without endotoxin. Reared concentration of about 90 kinds of pollutants were decided previously to the acute toxicity test in the presence of endotoxin. Endotoxin increased the lethal toxicities of HgCl2, NaSeO4, MnCl2, methanol, ethanol, propanol, butanol, pentanol, Span 60, Tween 60, ethylene glycol, propylene glycol and methyl cellosolve for killifish, and decreased the lethal toxicities of CuCl2, CuSO4, AgNO3 and Cu (CH3COO)2.

Journal

  • Eisei kagaku

    Eisei kagaku 32 (3), 191-196, 1986

    The Pharmaceutical Society of Japan

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