Anxiolytic and Antiseizure Effects of Sida tiagii Bhandri

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The central nervous system (CNS) pharmacological effects of ethylacetate extract (EAS) of Sida tiagii Bhandri collected from northern province (Rajasthan) of India were assessed by elevated plus-maze, pentobarbitone induced sleeping time, spontaneous motor activity, pentylenetetrazole-induced seizure, forced swim test and rotarod tests. The results of the present study demonstrated the CNS depressant potential, i.e., anxiolytic, antiseizure, reduction in spontaneous locomotion and potentiation of pentobarbital-induced hypnosis of the plant under investigation.

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