Identification and Determination of Cannabinoids in both Commercially Available and Cannabis Oils Stored Long Term
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- Yotoriyama Mamoru
- Tochigi Prefectural Institute of Public Health and Environment
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- Ishiharajima Eiji
- Tochigi Prefectural Institute of Public Health and Environment
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- Kato Yoko
- Tochigi Prefectural Institute of Public Health and Environment
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- Nagato Akiko
- Tochigi Prefectural Institute of Public Health and Environment
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- Sekita Setsuko
- Tsukuba Medicinal Plant Research Station, National Institute of Health Sciences
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- Watanabe Kazuhito
- Faculty of Pharmaceutical Sciences, Hokuriku University
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- Yamamoto Ikuo
- School of Pharmaceutical Sciences, Kyushu University of Health and Welfare
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Among cannabinoids (CNs) in two commercially available and long-term stored cannabis oils obtained from the seeds of Cannabis sativa L. in Japan, tetrahydrocannabinol (THC), canabidiol (CBD), cannabinol (CBN), and cannabichromene were identified and determined using high-performance thin-layer chromatography and capillary gas chromatography-mass speectrometry after partitioning extraction with n-hexane/acetonitrile. CNs were determined in two commercially available cannabis oils, designated “Hemp oil” (THC, 16.3 μg/g and CBN, 5.9 μg/g) and “Taima-yu” (CBD, 26.1 μg/g). The concentration of CBD in a cannabis oil that had been stored for 20 years was 107 ± 4 μg/g. However, no other CNs including THC were detected in the oil. The CBD content in the original oil was estimated to be about 130 μg/g from the determination values of the two periods. These results suggest that cannabis oils generally contain CNs to some extent. <br>
収録刊行物
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- JOURNAL OF HEALTH SCIENCE
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JOURNAL OF HEALTH SCIENCE 51 (4), 483-487, 2005
公益社団法人 日本薬学会
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詳細情報 詳細情報について
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- CRID
- 1390282679476110976
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- NII論文ID
- 10016658147
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- NII書誌ID
- AA11316464
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- ISSN
- 13475207
- 13449702
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- NDL書誌ID
- 7372469
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- CiNii Articles
- KAKEN
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- 抄録ライセンスフラグ
- 使用不可