Antifungal Activity of Diterpenes Isolated from <i>Metasequoia glyptostroboides</i> Hu et Cheng

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  • メタセコイアから単離されたジテルペンの抗糸状菌活性について
  • メタセコイア カラ タンリサレタ ジテルペン ノ コウ シジョウキン カッセイ

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Abstract

Labdane-type diterpenes 1 a, 2 a and 3 a were previously isolated from Metasequoia glyptostro-boides in our laboratory. These compounds were found to inhibit the spore germination of Pyricularia oryzae. The antifungal properties of 1 a, 2 a and 3 a, and their nine derivatives were examined to investigate the relationship between structure and antifungal activity.<br> The results suggested that the carboxyl group at the side chain and hydroxyl group at C-3 position were related to strong antifungal activity, and that the conjugated double bond and exomethylene group had little effect on the activity.

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  • Nippon Nōgeikagaku Kaishi

    Nippon Nōgeikagaku Kaishi 58 (9), 887-889, 1984

    Japan Society for Bioscience, Biotechnology, and Agrochemistry

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