Synchrotron Radiation Bioimaging using X-ray SATICON : Observation of tumor-derived small blood vessels

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Other Title
  • X線サチコンを使った放射光バイオイメージング : 癌増殖に伴う微小腫瘍血管の観察(高機能イメージセンサ)
  • X線サチコンを使った放射光バイオイメージング--癌増殖に伴う微小腫瘍血管の観察
  • Xセン サチコン オ ツカッタ ホウシャコウ バイオイメージング ガン ゾウショク ニ トモナウ ビショウ シュヨウ ケッカン ノ カンサツ

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Description

At SPring-8, a microangiography system with spatial resolution down to 10μm was developed using an X-ray direct-conversion type detector incorporating an X-ray SATICON pickup tube for biomedical imaging. An X-ray image is directly converted into an electric signal in a photoconductive layer without image blur. Because of the large depth of field, the microangiography system using a nearly parallel synchrotron radiation beam has advantages over light microscopes for imaging of internal structures of centimeter-sized objects with resolution in the micrometer range. Rat tumor blood vessels with diameters of 20-30μm in a vascular network produced by angiogenesis were visualized after contrast material injection.

Journal

  • ITE Technical Report

    ITE Technical Report 26.42 (0), 43-46, 2002

    The Institute of Image Information and Television Engineers

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