Training Software for the karyotyping using human chromosome images and its evaluation

DOI Web Site 3 References
  • KOGI Mieko
    Human Information System Laboratory, Kanazawa Institute of Technology
  • SUZUKI Akio
    Adoretech Corporation Co. Ltd.
  • KAWASE Shun
    Human Information System Laboratory, Kanazawa Institute of Technology
  • YOSHIZAWA Tatsuya
    Human Information System Laboratory, Kanazawa Institute of Technology

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Other Title
  • 画像を用いたヒト染色体核型分析のためのトレーニングソフトウエアの開発(視聴覚技術,ヒューマンインタフェース)
  • 画像を用いたヒト染色体核型分析のためのトレーニングソフトウェアの開発
  • ガゾウ オ モチイタ ヒト センショクタイカクガタ ブンセキ ノ タメ ノ トレーニングソフトウェア ノ カイハツ

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Abstract

In a karyotyping of human chromosomes as a typical analyzing method of the clinical pathology, we diagnose deficiency or abnormal on the basis of the forty six chromosomes arrayed in order. Results of a karyotyping determine for a choice of appropriate medicines treating the leukemia and are used to identify a cause of a congenital abnormality. To detect abnormality in a karyotyping, it is necessary to be well-trained and to have many experience of a karyotyping. Therefore, it takes a long time to train for beginners under hands-on supervision by skilled trainers. We developed a self-training software in which trainees repeatedly tried to be a standard alignment of human chromosome images. Evaluation of performance showed that all beginners greatly improved after 80 repetitions of the training. This indicates this training software is very effective to train beginners for a karyotyping.

Journal

  • ITE Technical Report

    ITE Technical Report 34.11 (0), 23-26, 2010

    The Institute of Image Information and Television Engineers

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