Development of an on-chip lensless fluorescence imaging device for single-molecule digital ELISA by using image processing

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  • デジタルELISA法に向けた画像処理によるレンズレスオンチップ蛍光検出デバイスの開発(高機能イメージセンシングとその応用)
  • ポスター講演 デジタルELISA法に向けた画像処理によるレンズレスオンチップ蛍光検出デバイスの開発
  • ポスター コウエン デジタル ELISAホウ ニ ムケタ ガゾウ ショリ ニ ヨル レンズレスオンチップ ケイコウ ケンシュツ デバイス ノ カイハツ

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We developed an ultra-small lensless on-chip fluorescence measurement device for a digital ELISA, which is expected as a method for very early diagnosis of cancer or infection with a virus. We succeeded in high-resolution observation by the image restoration with deconvolution processing. The field of view can be easily extended due to its lensless structure. In the future, we apply it to a digital ELISA system, which has detection sensitivity of million times higher than the conventional ELISA method, and aim to realize a molecular measurement system with ultra-high sensitive and quantitative performance.

Journal

  • ITE Technical Report

    ITE Technical Report 37.22 (0), 41-44, 2013

    The Institute of Image Information and Television Engineers

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