菌類によるアルカロイドおよび関連物質の生産(第1報)

DOI
  • 阿部 又三
    東京教育大学農学部
  • 大和谷 三郎
    武田薬品工業株式会社研究開発本部醗酵生産物研究所
  • 山野 藤吾
    武田薬品工業株式会社研究開発本部醗酵生産物研究所
  • 高津 嘉春
    武田薬品工業株式会社研究開発本部醗酵生産物研究所
  • 山田 三郎
    武田薬品工業株式会社研究開発本部醗酵生産物研究所

書誌事項

タイトル別名
  • Production of Alkaloids and Related Substances by Fungi Part I
  • Examination of Filamentous Fungi for their Ability of Producing Ergot Alkaloids
  • 各種糸状菌類の麦角アルカロイド生産性

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抄録

The strains of some 1, 000 species of filamentous fungi were examined for their ability to produce ergot alkaloids in surface and submerged cultures under certain conditions. Besides Asp. fumigatus strain, 19 strains belonging widely to the classes Phycomycetes, Ascomycetes, Basidiomycetes and Fungi imperfecti were found to have a definite ability of producing clavine alkaloids: The alkaline ether extracts obtained from the cultures of these strains gave a positive color test with Ehrlich's reagent, and paper chromatography of each of these extracts showed this to be due to a number of substances, at least one of which was identical in RF value with either elymoclavine, agroclavine (secaclavine), festuclavine (pyroclavine or costaclavine), fumigaclavine A, B or C.

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