Production of Alkaloids and Related Substances by Fungi Part I

DOI
  • ABE Matazo
    Faculty of Agriculture, Tokyo University of Education
  • YAMATODANI Saburo
    Microbiological Research Laboratories, Research and Development Division, Takeda Chemical Industries, Ltd.
  • YAMANO Togo
    Microbiological Research Laboratories, Research and Development Division, Takeda Chemical Industries, Ltd.
  • KOZU Yoshiharu
    Microbiological Research Laboratories, Research and Development Division, Takeda Chemical Industries, Ltd.
  • YAMADA Saburo
    Microbiological Research Laboratories, Research and Development Division, Takeda Chemical Industries, Ltd.

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Other Title
  • 菌類によるアルカロイドおよび関連物質の生産(第1報)
  • Examination of Filamentous Fungi for their Ability of Producing Ergot Alkaloids
  • 各種糸状菌類の麦角アルカロイド生産性

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Description

The strains of some 1, 000 species of filamentous fungi were examined for their ability to produce ergot alkaloids in surface and submerged cultures under certain conditions. Besides Asp. fumigatus strain, 19 strains belonging widely to the classes Phycomycetes, Ascomycetes, Basidiomycetes and Fungi imperfecti were found to have a definite ability of producing clavine alkaloids: The alkaline ether extracts obtained from the cultures of these strains gave a positive color test with Ehrlich's reagent, and paper chromatography of each of these extracts showed this to be due to a number of substances, at least one of which was identical in RF value with either elymoclavine, agroclavine (secaclavine), festuclavine (pyroclavine or costaclavine), fumigaclavine A, B or C.

Journal

  • Nippon Nōgeikagaku Kaishi

    Nippon Nōgeikagaku Kaishi 41 (2), 68-71, 1967

    Japan Society for Bioscience, Biotechnology, and Agrochemistry

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