多孔質膜内に形成されたりん脂質膜のイオン選択性

書誌事項

タイトル別名
  • Ion Selectivity of Phospholipid Membranes Constructed in a Porous Membrane
  • タコウシツ マク ナイ ニ ケイセイサレタ リン シシツ マク ノ イオン セ
公開日
1976
DOI
  • 10.1271/nogeikagaku1924.50.2_91
公開者
公益社団法人 日本農芸化学会

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説明

The membrane potential of “Millipore” filters in which the thin membranes of phospho-lipids and the liquid membranes consisting of phospholipids and oleyl alcohol were con-structed was measured in the mixture of potassium and sodium chloride solutions in the presence of an ionophore such as valinomycin or gramicidin D. From the results obtained, the potassium ion selectivity against the sodium ion for these lipid membranes was discussed. The phospholipids (or their analogs) used were phosphatidyl choline (PC), phosphatidyl ethanolamine (PE), phosphatidyl serine (PS), dioleyl phosphate (DOP) and distearyl phosphite (DSP).<br> The permeability ratio (PK/PNa) of the filters containing the thin lipid membranes made of PC or DOP is in the range of 1.7 to 1.9 in the presence of the ionophores. In the case of the liquid membranes, in general, the permeability ratio is higher than that in the case of the thin membranes. For the liquid membranes in the absence of ionophores, the ion selectivity is somewhat observed. The selectivity increases fairly on addition of valinomycin, whereas it does not appreciably increase on addition of gramicidin D. When the quantity of lipid solution contained in the filter is reduced, the permeability ratio of the filters in the presence of the ionophores in general decreases.

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