Direct Alkylation of 3-Hydroxy-ϒ-pyrone at the 2-Position
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- KAWASE Katsuhiro
- Fine Chemicals Department, R. K. Mizuno Sporting Goods Co., Ltd.
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- HAYASHI Keijiro
- Fine Chemicals Department, R. K. Mizuno Sporting Goods Co., Ltd.
Bibliographic Information
- Other Title
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- 3-Hydroxy-ϒ-pyrone 2位の直接アルキル化
- 3-Hydroxy-ガンマ-pyrone2イ ノ チョクセツ アルキルカ Maltol オヨビ ソノ カンレン カゴウブツ ノ ゴウセイ 2
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Description
The method described in literature for alkylating 3-hydroxy-ϒ-pyrone (pyromeconic acid) at the 2-position consists of the reduction of the hydroxylic intermediates or the Mannich base which were derived from the reaction with aldehydes.<br> The application of this method is limited, for example, the introduction of isopropyl or phenyl groups by this means is impossible.<br> The present authors have developed a novel method for direct alkylation of pyromeconic acid at the 2-position by refluxing the glacial acetic acid solution of pyromeconic acid in the presence of diacyl peroxides or aroyl peroxides.<br> A radical mechanism seems to be operative in the present reaction.
Journal
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- Nippon Nōgeikagaku Kaishi
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Nippon Nōgeikagaku Kaishi 46 (7), 335-339, 1972
Japan Society for Bioscience, Biotechnology, and Agrochemistry
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Details 詳細情報について
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- CRID
- 1390282679510533376
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- NII Article ID
- 130001222760
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- NII Book ID
- AN00196191
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- COI
- 1:CAS:528:DyaE3sXktlWqug%3D%3D
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- ISSN
- 18836844
- 00021407
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- NDL BIB ID
- 7622780
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed