The Percutaneous Absorption of <sup>35</sup>S-Acetyl-L-Methionine and L-Serine in Rabbit

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  • MATSUMOTO Norikazu
    Department of Agricultural Chemistry, Tokyo University of Agriculture
  • OZAWA Yasuo
    Department of Agricultural Chemistry, Tokyo University of Agriculture
  • HASEGAWA Tadao
    Department of Agricultural Chemistry, Tokyo University of Agriculture
  • SUZUKI Takao
    Department of Agricultural Chemistry, Tokyo University of Agriculture

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Other Title
  • ウサギにおける?Q３５?RＳ‐アセチルＬ‐メチオニンとＬ‐セリンの経皮吸収
  • ウサギ ニ オケル 35S アセチル L メチオニン ト L セリン ノ ケイ

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Description

The authors had reported that L-cysteine probably was formed from acetyl-L-methionine and L-serine through cystathionine pathway by the skin enzyme of rabbit, and the solution composed of acetyl-L-methionine and L-serine exhibited the effectiveness to the hair growth in rabbit. This report shows that, by the application of 35S-acetyl-L-methionine and L-serine to the skin of rabbit and in vitro analysis of the metabolites of 35S-compounds, 35S-acetyl-L-methionine was absorbed into the hair tissues for many hours, and half 35S-L-cystine was formed in vitro and in vivo. When total amount of 35S in the hair was measured, the radiochemical activities were cleary shown as almost 35S-L-cystine.

Journal

  • Nippon Nōgeikagaku Kaishi

    Nippon Nōgeikagaku Kaishi 51 (7), 423-427, 1977

    Japan Society for Bioscience, Biotechnology, and Agrochemistry

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