Studies on the Guanosine Degrading System in Bacteria Part II

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  • ISHIDA Yasunari
    Microbiological Research Laboratories, Research and Development Division, Takeda Chemical Industries, Ltd.
  • SHIRAFUJI Hideo
    Microbiological Research Laboratories, Research and Development Division, Takeda Chemical Industries, Ltd.
  • KIDA Makoto
    Microbiological Research Laboratories, Research and Development Division, Takeda Chemical Industries, Ltd.
  • YONEDA Masahiko
    Microbiological Research Laboratories, Research and Development Division, Takeda Chemical Industries, Ltd.

Bibliographic Information

Other Title
  • 細菌によるグアノシンの分解について(第2報)
  • Guanosine deaminase ニ ヨル グアノシン ヨリ キサントシン セイセイ ニ ツイテ
  • The Formation of Xanthosine from Guanosine
  • Guanosine deaminaseによるグアノシンよりキサントシンの生成について

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Description

The authors previously reported that Pseudomonas convexa No. 149 seemed to produce a new enzyme, guanosine deaminase which directly deaminates guanosine producing xanthosine.<br> In this paper, studies were made on several culture conditions for the production of guanosine deaminase. Addition of purine and pyrimidine nucleosides except thymidine to the cultured media, repressed the production of guanosine deaminase. No repression, however, occurred by the addition of purine and pyrimidine bases. This enzyme was produced at stationary phase and no activity was found in the supernatant of broth.<br> Xanthosine formed by the deamination of guanosine with the enzyme was crystallized and identified by the infra-red absorption spectrum.

Journal

  • Nippon Nōgeikagaku Kaishi

    Nippon Nōgeikagaku Kaishi 43 (1), 6-12, 1969

    Japan Society for Bioscience, Biotechnology, and Agrochemistry

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