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- Nabetani Makoto
- Department of Pediatrics, Kure Mutual Aid Hospital
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- Tsuneishi Shuichi
- Department of Pediatrics, Kure Mutual Aid Hospital
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- Kugo Masaaki
- Department of Pediatrics, Kure Mutual Aid Hospital
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- Konishi Hideki
- Department of Pediatrics, Saeki Chuou Hospital
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- Yamazaki Takemi
- Department of Pediatrics, Kure Mutual Aid Hospital
Bibliographic Information
- Other Title
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- 生後２カ月時より発症し著明な脳萎縮を伴った後天性サイトメガロウイルス感染症の１例
Description
A 2-month- old girl had focal tonic convulsions. Brain CT showed no abnormalities on admission. Three weeks later she got a severe epileptic status. T1-weighted MRI demonstrated low intensity areas in the right occipital and left frontal regions, and enhanced CT demonstrated low density areas in the same region. An increase of CMV antibody titer in serum suspected CMV infection associated with brain infarction. Then γ-globulin was given in addition to PB, CBZ, and VPA, resulting in supression of seizures. At 9 months of age, she had right tonic herniconvulsions. An increase of CMV IgM antibody titer showed reactivation of CMV infection. Acyclovir and γ-globulin were given, and her seizures were controlled. However, she showed progressive motor disability with spastic muscle tonus. CT and MRI showed a severe progressive atrophy of the cerebrum and brain stem.
Journal
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- NO TO HATATSU
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NO TO HATATSU 25 (1), 76-80, 1993
THE JAPANESE SOCIETY OF CHILD NEUROLOGY
