含硫アミノ酸類の皮膚面よりの養毛効果

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  • Promotion of Hair Growth by Applying Sulfur Amino Acids and Other Things to the Skin
  • ガンリュウアミノ サンルイ ノ ヒフメン ヨリ ノ ヨウモウ コウカ

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In the preceding papers, we proposed the following explanation: L-cysteine formed from L-methionine and L-serine through cystathionine pathway in the skin tissues, and L-methionine and L-serine exhibited the effectiveness to the hair growth. However L-methionine has not the practical value because of the illsmelling compound. Whereas acetyl-L-methionine was recognized as the odorless compound by the preservation test, acetyl-L-methionine was used for experiments of L-cysteine formation instead of L-meth-ionine. In addition, another amino acids, peptide and nucleoside were applied to the same purpose. The test of hair growth were made by applying the amino acids solution on the rabbit skin, that is, 0.2% L-methionine, L-serine, 0.2% acetyl-L-methionine, L-serine, 0.2% glutathione, 0.2% L-cysteine, 0.2% L-methionine, L-serine and inosine were made up as the amino acids solution respectively. Results showed, L-methionine, L-serine solution was very efficacious, and acetyl-L- methionine, L-serine solution L-cys-teine solution, L-methionine, L-serine and inosine solution were also efficacious, but glutathione solution showed the inhibitory actions to both of the growth of hair and hair roots.

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