Discrimination of Albumin and Lysozyme-Adsorption Characteristics on Two Differently-Originated Apatites

  • Akazawa Toshiyuki
    Hokkaido Industrial Research Institute
  • Kobayashi Masayoshi
    Department of Chemical System Engineering, Kitami Institute of Technology
  • Kanno Tohru
    Department of Chemical System Engineering, Kitami Institute of Technology
  • Kodaira Kohei
    Division of Materials Science and Engineering, Graduate School of Engineering, Hokkaido University

Abstract

Two kinds of hydroxyapatite (HAp) originated from cattle bones and reagents displayed different adsorption behavior of albumin on the C-sites and lysozyme on the P-sites of the HAp surface, which was strongly influenced by the basic strength of the C-sites and the acid strength of the P-sites as well as the total amount or surface proportion of the two sites, depending on the heat-treatment temperature of the HAp’s.

Journal

  • Chemistry Letters

    Chemistry Letters 25 (9), 779-780, 1996

    The Chemical Society of Japan

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