Solvent-free Imino-Aldol Three-component Couplings on a Conveniently-prepared and Reusable Phosphoric Acid-Silica Gel Support

DOI 25 References
  • Lock Sandra
    Department of Chemistry, Faculty of Integrated Arts and Sciences, University of Tokushima
  • Miyoshi Norikazu
    Department of Chemistry, Faculty of Integrated Arts and Sciences, University of Tokushima
  • Wada Makoto
    Department of Chemistry, Faculty of Integrated Arts and Sciences, University of Tokushima

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Abstract

A new solvent-free procedure for the synthesis of β-amino carbonyl compounds in generally moderate to excellent yields has been developed. Three-component Mannich-type couplings between aldehydes (aromatic, aliphatic, alicyclic, and heterocyclic), aromatic amines and silyl enol equivalents proceeded smoothly on a conveniently prepared and reusable phosphoric acid-silica gel solid support.

Journal

  • Chemistry Letters

    Chemistry Letters 33 (10), 1308-1309, 2004

    The Chemical Society of Japan

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Details

  • CRID
    1390282679558864256
  • NII Article ID
    10013658398
  • NII Book ID
    AA00603318
  • DOI
    10.1246/cl.2004.1308
  • ISSN
    13480715
    03667022
  • Text Lang
    en
  • Data Source
    • JaLC
    • Crossref
    • CiNii Articles
  • Abstract License Flag
    Disallowed

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