Solvent-free Imino-Aldol Three-component Couplings on a Conveniently-prepared and Reusable Phosphoric Acid-Silica Gel Support

DOI PDF 参考文献25件
  • Lock Sandra
    Department of Chemistry, Faculty of Integrated Arts and Sciences, University of Tokushima
  • Miyoshi Norikazu
    Department of Chemistry, Faculty of Integrated Arts and Sciences, University of Tokushima
  • Wada Makoto
    Department of Chemistry, Faculty of Integrated Arts and Sciences, University of Tokushima

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抄録

A new solvent-free procedure for the synthesis of β-amino carbonyl compounds in generally moderate to excellent yields has been developed. Three-component Mannich-type couplings between aldehydes (aromatic, aliphatic, alicyclic, and heterocyclic), aromatic amines and silyl enol equivalents proceeded smoothly on a conveniently prepared and reusable phosphoric acid-silica gel solid support.

収録刊行物

  • Chemistry Letters

    Chemistry Letters 33 (10), 1308-1309, 2004

    公益社団法人 日本化学会

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