Metabolic Interaction of Bittern and Various Trace Elements in Mice by Using Multi-tracer Technology and Gamma-ray Emission Imaging System (GREI) as a New Modality for Multiple Molecular Imaging

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  • Hiromura Makoto
    Multiple Molecular Imaging Research Laboratory, RIKEN Kobe Institute, Center for Molecular Imaging Science
  • Kanayama Yosuke
    Multiple Molecular Imaging Research Laboratory, RIKEN Kobe Institute, Center for Molecular Imaging Science
  • Igarashi Kaori
    Multiple Molecular Imaging Research Laboratory, RIKEN Kobe Institute, Center for Molecular Imaging Science
  • Haba Hiromitsu
    RIKEN Wako Institute, Nishina Center for Accelerator-Based Science, Nishina Center for Accelerator-Based Science
  • Enomoto Shuichi
    Multiple Molecular Imaging Research Laboratory, RIKEN Kobe Institute, Center for Molecular Imaging Science RIKEN Wako Institute, Nishina Center for Accelerator-Based Science, Nishina Center for Accelerator-Based Science Department of Pharmaceutical Analytical Chemistry, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University

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  • にがり成分の生体内ダイナミクスと代謝吸収過程のイメージング
  • ニ ガリ セイブン ノ セイタイナイ ダイナミクス ト タイシャ キュウシュウ カテイ ノ イメージング

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Abstract

Metabolic interaction of bittern water and various trace elements in mice by using multi-tracer technology and Gamma-ray Emission Imaging System (GREI) as a new modality of multiple molecular imaging.<br>Recently, biotrace elements (elements that are essential to our bodies in minute amounts) have caught our attention, as health has become an important issue to many peoples' lives. The metabolism and dispersion of many biotrace elements may be analyzed using multi-tracer technology. Multi-tracer technology allows simultaneous tracing of various radioactive isotopes (RI). By administrating a multi-tracer solution containing various RI into a living organism, the activity of these RI can be detected using a high purity Ge detector or Gamma-ray Emission Imaging (GREI). In this review, we discuss the biological dynamics of bittern water using multitracer technology and multiple molecular imaging by use of semiconductor Compton cameras.

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