橈骨動脈圧波形から導いた拡張型動脈系電気回路モデルによる循環動態の非侵襲的評価法

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タイトル別名
  • Noninvasive Method for Circulatory System by an Extended Electric Circuit Arterial Model Combined with Radial Artery Pressure Wave-Form Measurement
  • トウコツ ドウミャクアツ ハケイ カラ ミチビイタ カクチョウガタ ドウミャク

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One of the well-known model representing artery system is the four-factor concentrated constant circuit model. It consists from the four factors: central and peripheral resistance, compliance and inertia of blood. In the former report, we proposed a method in which the four concentrated circuit constants can be quantitatively determined. The circulatory parameters calculated by this method before and after sympathetic β-blockade coincided well with the supposed changes of the parameters. However, this model couldn't evaluated the compliance divided in central and peripheral part. In this paper we introduced an approximated radial artery pressure wave-form equation which is adjustable to wide variation of the real measured pressure wave-form. The equation consists of two terms. The first is dominant at the earlier stage of a wave, and the second is at the later stage. We introduced two equivalent circuits corresponding to each terms, then integrated them to unique five-factor constant electrical circuit model by the principle of superposition, in which two capacitors corresponding to central and peripheral compliance are included. For the input voltage to the circuit, we use the wave-form corresponding to the left ventricular pressure approximated by the sequences of half-sine-waves. For the inspection of propriety of this circuit model, we measured the following effects before and after the dosage of vasodilator drug. The responses on radial artery pressure wave-form, average blood pressure, difference between max. and min. blood pressure and stroke volume, can be sufficiently explained by this circuit model qualitatively.

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