書誌事項
- タイトル別名
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- Shear Loading and Red Blood Cells' Deformability
- センダン フカ ト セッケッキュウ ヘンケイノウ シンドウ ジュンクエット ナガレ ニ タイスル ヘンケイ オウトウ カイセキ
- Analyses of Dynamic Responses to an Oscillating Quasi-Couette Shear Flow
- 振動準クエット流れに対する変形応答解析
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抄録
We successfully developed the system which enabled to directly evaluate the red blood cells' (RBCs') deformability under the oscillatory quasi-Couette shear flow. The oscillatory quasi-Couette flow was generated in the RBCs' suspension fluid that was placed in the narrow gap of 30 micrometers between the two parallel glass plates, where the upper plate was forced to make a reciprocating motion by a slider-crank mechanism with respect to the stationary bottom plate. The human normal intact RBCs showed unique shape change response containing the abrupt elastic deformation phase and the delayed visco-elastic shape recovery phase to the sinusoidally changing shear stress. The system successfully detected the shear stress induced deterioration of RBCs' deformability, and also the deteriorated deformability of RBCs which were acquired from healthy adult volunteers comparing with those from the aged diabetes patients. The proposed system will possibly clarify the pathophysiological status of blood cells related to various cardiovascular or blood diseases.
収録刊行物
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- 可視化情報学会誌
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可視化情報学会誌 27 (Supplement1), 143-146, 2007
社団法人 可視化情報学会
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詳細情報 詳細情報について
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- CRID
- 1390282679597203968
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- NII論文ID
- 10019519236
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- NII書誌ID
- AN10374478
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- ISSN
- 1884037X
- 09164731
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- NDL書誌ID
- 8891528
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可