Inhibitory Effects of Shouseiryu-to on Two-Stage Carcinogenesis-2-Anti-tumor-promoting Activities of Lignans from Asiasarum heterotropoides var.mandshuricum
書誌事項
- タイトル別名
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- Inhibitory Effects of Shouseiryu-to on Two-Stage Carcinogenesis. II. Anti-tumor-promoting Activities of Lignans from Asiasarum heterotropoides var. mandshuricum.
- Inhibitory Effects of Shouseiryu-to on
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説明
Two lignans, asarinin (6) and xanthoxylol (7), were isolated from the radix of Asiasarum heterotropoides var. mandshuricum, which consist of a kampo prescription, Shouseiryu-to, as inhibitors of Epstein-Barr virus early antigen (EBV-EA) activation induced by 12-O-tetradecanoylphorbol-13-acetate (TPA). These lignans also exhibited remarkable inhibitory effects on a two-stage carcinogenesis test of mouse skin and pulmonary tumors. Furthermore, it was confirmed that these hydrophobic lignans dissolved in the water decoction of Shouseiryu-to, and these lignans might be among the active consituents of this kampo prescription in terms of its anti-tumor-promoting activity.
収録刊行物
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- Ｂｉｏｌｏｇｉｃａｌ ＆ Ｐｈａｒｍａｃｅｕｔｉｃａｌ Ｂｕｌｌｅｔｉｎ
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Ｂｉｏｌｏｇｉｃａｌ ＆ Ｐｈａｒｍａｃｅｕｔｉｃａｌ Ｂｕｌｌｅｔｉｎ 20 (7), 776-780, 1997
公益社団法人 日本薬学会
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詳細情報 詳細情報について
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- CRID
- 1390282679597739648
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- NII論文ID
- 110003639146
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- NII書誌ID
- AA10885497
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- COI
- 1:CAS:528:DyaK2sXkslygtLg%3D
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- ISSN
- 13475215
- 09186158
- http://id.crossref.org/issn/09186158
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- NDL書誌ID
- 4260462
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- PubMed
- 9255419
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- 本文言語コード
- en
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- 資料種別
- journal article
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- データソース種別
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- JaLC
- NDLサーチ
- Crossref
- PubMed
- CiNii Articles
- OpenAIRE
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- 抄録ライセンスフラグ
- 使用不可
