In Vitro Glucuronidation of 25-Hydroxyvitamin D3 and Its Pro-form.
書誌事項
- タイトル別名
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- In Vitro Glucuronidation of 25-Hydroxyv
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説明
In vitro glucuronidation of 25-hydroxyvitamin D3 and its pro-form has been investigated by means of HPLC with UV detection. Although both substrates gave 3- and 25-glucuronides in the presence of the ray liver microsomal fraction and uridine-5'-diphosphoglucuronic acid, 25-hydroxyvitamin D3 and its pro-form yielded 3- and 25-glucuronide as the main product, respectively. The latter glucuronide is the one in which the tert-hydroxy group is conjugated. Each glucuronide was identified by its chromatographic behavior in comparison with an authentic sample and data obtained from liquid chromatography/mass spectrometry (LC/MS) using atmospheric pressure chemical ionization.
収録刊行物
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- Biological & Pharmaceutical Bulletin
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Biological & Pharmaceutical Bulletin 20 (6), 596-600, 1997
公益社団法人 日本薬学会
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詳細情報 詳細情報について
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- CRID
- 1390282679599284096
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- NII論文ID
- 110003639108
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- NII書誌ID
- AA10885497
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- COI
- 1:CAS:528:DyaK2sXkt1Ohtbs%3D
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- ISSN
- 13475215
- 09186158
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- NDL書誌ID
- 4240331
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- PubMed
- 9212974
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可