Inhibition of the Metallo-β-lactamase Produced from Serratia marcescens by Thiol Compounds
書誌事項
- タイトル別名
-
- Inhibition of the Metallo-.BETA.-lactamase Produced from Serratia marcescens by Thiol Compounds.
- Inhibition of the Metallo ベータ lactamase
この論文をさがす
抄録
Low molecular weight thiol compounds have been found to be strong inhibitors of metallo-β-lactamase (IMP-1) produced by Serratia marcescens TN9106, which was expressed by Echerichia coli JM109 cells. Mercaptoacetic acid and 2-mercaptopropionic acid strongly and competitively inhibited IMP-1 with Ki of 0.23 and 0.19 μM, respectively. 2-Mercaptoethanol reversibly inhibited IMP-1 but did not show simple competitive inhibition.
収録刊行物
-
- Ｂｉｏｌｏｇｉｃａｌ ＆ Ｐｈａｒｍａｃｅｕｔｉｃａｌ Ｂｕｌｌｅｔｉｎ
-
Ｂｉｏｌｏｇｉｃａｌ ＆ Ｐｈａｒｍａｃｅｕｔｉｃａｌ Ｂｕｌｌｅｔｉｎ 20 (11), 1136-1140, 1997
公益社団法人 日本薬学会
- Tweet
詳細情報 詳細情報について
-
- CRID
- 1390282679599579264
-
- NII論文ID
- 110003638966
-
- NII書誌ID
- AA10885497
-
- COI
- 1:CAS:528:DyaK2sXnslais7s%3D
-
- ISSN
- 13475215
- 09186158
- http://id.crossref.org/issn/09186158
-
- NDL書誌ID
- 4346294
-
- PubMed
- 9401719
-
- 本文言語コード
- en
-
- データソース種別
-
- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
-
- 抄録ライセンスフラグ
- 使用不可
