Potent Antihepatotoxic Activity of Dicaffeoyl Quinic Acids from Propolis.

BASNET Purusotam, MATSUSHIGE Katsumichi, HASE Koji, KADOTA Shigetoshi, NAMBA Tsuneo

doi:10.1248/bpb.19.655

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Description

Hepatoprotective activity guided chemical analyses led to the isolation of two dicaffeoyl quinic acid derivatives, methyl 3, 4-di-O-caffeoyl quinate (1) and 3, 4-di-O-caffeoyl quinic acid (2) from water extract of propolis, and their structures were determined by the use of 2D NMR. These compounds were stronger antihepatotoxic agents than glucyrrhizin.

Journal

Biological and Pharmaceutical Bulletin

Biological and Pharmaceutical Bulletin 19 (4), 655-657, 1996

The Pharmaceutical Society of Japan

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Details 詳細情報について

CRID: 1390282679599629568

NII Article ID: 110003641236

NII Book ID: AA10885497

DOI: 10.1248/bpb.19.655

COI: 1:CAS:528:DyaK28XisFSht7s%3D

ISSN: 13475215; 09186158; http://id.crossref.org/issn/09186158

PubMed: 9132180

Web Site: http://www.jstage.jst.go.jp/article/bpb1993/19/4/19_4_655/_pdf; https://search.jamas.or.jp/link/ui/1996187935

Text Lang: en

Article Type: journal article

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