Susceptibilities of Methicillin-Resistant Staphylococcus aureus Isolates to Seven Biocides

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  • Narui Koji
    Department of Microbiology, School of Pharmacy, Tokyo University of Pharmacy and Life Science
  • Takano Mitsuo
    Department of Pharmacy, Hokushin General Hospital
  • Noguchi Norihisa
    Department of Microbiology, School of Pharmacy, Tokyo University of Pharmacy and Life Science
  • Sasatsu Masanori
    Department of Microbiology, School of Pharmacy, Tokyo University of Pharmacy and Life Science

書誌事項

公開日
2007
DOI
  • 10.1248/bpb.30.585
公開者
公益社団法人 日本薬学会

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説明

Minimum bactericidal concentrations (MBCs) of seven biocides for 42 methicillin-resistant Staphylococcus aureus (MRSA) isolates at 5, 30, or 180 min, for hand scrubs or soaks, isolated in 2003 in Japan were determined. The MBC values of glutaraldehyde, povidone iodine, and ethanol were lower than the user concentrations in all exposure times. However, at 5 min exposure of sodium hypochlorite, benzalkonium chloride, alkyldiaminoethylglycine hydrochloride, and chlorhexidine digluconate some strains showed higher MBC values than the user concentrations. These results indicated the possibility that MRSA survived under proper user concentration conditions and exposure time.

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