N-trans-Feruloyltyramine as a Melanin Biosynthesis Inhibitor
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- Efdi Mai
- Department of Chemistry, Faculty of Engineering, Gifu University
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- Ohguchi Kenji
- Gifu International Institute of Biotechnology
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- Akao Yukihiro
- Gifu International Institute of Biotechnology
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- Nozawa Yoshinori
- Gifu International Institute of Biotechnology
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- Koketsu Mamoru
- Division of Instrumental Analysis, Life Science Research Center, Gifu University
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- Ishihara Hideharu
- Department of Chemistry, Faculty of Engineering, Gifu University
書誌事項
- 公開日
- 2007
- 資源種別
- journal article
- DOI
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- 10.1248/bpb.30.1972
- 公開者
- 公益社団法人 日本薬学会
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説明
In this study, we examined the effect of N-trans-feruloyltyramine (FA) on melanogenesis in mouse B16 melanoma cells. Melanogenesis was inhibited by FA in a dose-dependent manner. FA exhibited a greater potency than kojic acid as a standard inhibitor of melanogenesis. Moreover, treatment of B16 melanoma cells with FA was found to cause marked decreases in the expression levels of tyrosinase. FA-induced downregulation of tyrosinase resulted in suppression of melanin biosynthesis in murine B16 melanoma cells.
収録刊行物
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- Ｂｉｏｌｏｇｉｃａｌ ＆ Ｐｈａｒｍａｃｅｕｔｉｃａｌ Ｂｕｌｌｅｔｉｎ
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Ｂｉｏｌｏｇｉｃａｌ ＆ Ｐｈａｒｍａｃｅｕｔｉｃａｌ Ｂｕｌｌｅｔｉｎ 30 (10), 1972-1974, 2007
公益社団法人 日本薬学会
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詳細情報 詳細情報について
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- CRID
- 1390282679601839104
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- NII論文ID
- 110006436388
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- NII書誌ID
- AA10885497
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- ISSN
- 13475215
- 09186158
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- HANDLE
- 20.500.12099/31908
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- NDL書誌ID
- 8919665
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- PubMed
- 17917275
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- 本文言語コード
- en
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- 資料種別
- journal article
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- データソース種別
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- JaLC
- IRDB
- NDLサーチ
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