Antifungal Activity of Hinokitiol-Related Compounds on Wood-Rotting Fungi and Their Insecticidal Activities.
書誌事項
- 公開日
- 2000
- 資源種別
- journal article
- DOI
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- 10.1248/bpb.23.995
- 公開者
- 公益社団法人 日本薬学会
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説明
Hinokitiol (β-thujaplicin), β-dolabrin and γ-thujaplicin isolated from Thujopsis dolabrata SIEB, et ZUCC. var hondai MAKINO showed antifungal activities against all of the wood-rotting fungi examined. The antifungal activity of three compounds on Daedalea dickinsii IFO-4979 was especially strong, their mininum inhibitory concentration (MIC) values being 0.2 μg/ml. Their antifungal activities on D. dickinsii IFO-4979 were as high as that of amphotericin B used as a positive control. Three compounds had strong insecticidal activities on Tyrophagus putrescentiae [50%-lethal concentration (LC50 : g/m2) 0.25 in hinokitiol, 0.02 in β-dolabrin and γ-thujaplicin]. Their insecticidal activities were higher than that of N, N-diethyl-m-toluamide (DEET, LC50 : 1.46 g/m2) used as a positive control. Three compopunds also showed strong insecticidal activity on Coptotermes formosanus [LC50 (g/m2) 0.07 in hinokitiol, 0.05 in β-dolabrin and γ-thujaplicin], although their insecticidal activities were much lower than that of commerical chloropyrifos (LC50 : 0.00016 g/m2).
収録刊行物
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- Biological & Pharmaceutical Bulletin
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Biological & Pharmaceutical Bulletin 23 (8), 995-997, 2000
公益社団法人 日本薬学会
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詳細情報 詳細情報について
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- CRID
- 1390282679603687552
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- NII論文ID
- 110003640109
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- NII書誌ID
- AA10885497
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- COI
- 1:CAS:528:DC%2BD3cXlsFamsL0%3D
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- ISSN
- 13475215
- 09186158
- https://id.crossref.org/issn/09186158
- http://id.crossref.org/issn/09186158
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- NDL書誌ID
- 5431377
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- PubMed
- 10963310
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- 本文言語コード
- en
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- 資料種別
- journal article
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- データソース種別
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- JaLC
- NDLサーチ
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- PubMed
- CiNii Articles
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- 使用不可