β3-Adrenoceptor Is Involved in the Inhibition of Small Intestinal Motility Due to Restraint Stress in Rats
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- TSUKADA Fumitake
- Department of Radiopharmacy, Tohoku Pharmaceutical University
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- SUGAWARA Mika
- Department of Radiopharmacy, Tohoku Pharmaceutical University
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- SAWAMURA Kuniko
- Department of Radiopharmacy, Tohoku Pharmaceutical University
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- OHUCHI Yukie
- Department of Radiopharmacy, Tohoku Pharmaceutical University
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- KOHNO Hiroyuki
- Department of Radiopharmacy, Tohoku Pharmaceutical University
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- OHKUBO Yasuhito
- Department of Radiopharmacy, Tohoku Pharmaceutical University
書誌事項
- タイトル別名
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- .BETA.3-Adrenoceptor Is Involved in the Inhibition of Small Intestinal Motility Due to Restraint Stress in Rats.
- ベータ 3 Adrenoceptor Is Involved in the Inhibition of Small Intestinal Motility Due to Restraint Stress in Rats
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抄録
We have reported that acute restraint stress inhibits small intestinal motility in rats. In order to clarify this inhibitory mechanism, we examined the effects of α- and β-adrenergic antagonists on the inhibition of small intestinal motility induced by restraint stress. This inhibition underwent recovery by propranolol (β1/β2-antagonist) or SR59230A (β3-antagonist), but not by atenolol (β1-antagonist), ICI-118,551 (β2-antagonist), prazosin (α1-antagonist) or yohimbine (α2-antagonist). These results suggest that β3-adrenoceptors play an important role in the inhibition of small intestinal motility caused by restraint stress.
収録刊行物
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- Ｂｉｏｌｏｇｉｃａｌ ＆ Ｐｈａｒｍａｃｅｕｔｉｃａｌ Ｂｕｌｌｅｔｉｎ
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Ｂｉｏｌｏｇｉｃａｌ ＆ Ｐｈａｒｍａｃｅｕｔｉｃａｌ Ｂｕｌｌｅｔｉｎ 24 (9), 995-997, 2001
公益社団法人 日本薬学会
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詳細情報 詳細情報について
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- CRID
- 1390282679603833344
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- NII論文ID
- 110003638606
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- NII書誌ID
- AA10885497
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- COI
- 1:CAS:528:DC%2BD3MXmsFyksrs%3D
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- ISSN
- 13475215
- 09186158
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- NDL書誌ID
- 5892722
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- PubMed
- 11558583
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可