Total Peroxynitrite Scavenging Capacity of Phenylethanoid and Flavonoid Glycosides from the Flowers of Buddleja officinalis
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- Tai Bui Huu
- Institute of Natural Products Chemistry, VAST College of Pharmacy, Chungnam National University
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- Jung Bong Yong
- College of Pharmacy, Chungnam National University RCTCP, Chungnam National University
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- Cuong Nguyen Manh
- Institute of Natural Products Chemistry, VAST
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- Linh Pham Thuy
- Institute of Chemistry, VAST
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- Tung Nguyen Huu
- College of Pharmacy, Chungnam National University
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- Nhiem Nguyen Xuan
- College of Pharmacy, Chungnam National University
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- Huong Tran Thu
- Institute of Natural Products Chemistry, VAST
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- Anh Ngo Thi
- Institute of Natural Products Chemistry, VAST
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- Kim Jeong Ah
- College of Pharmacy, Chungnam National University
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- Kim Sang Kyum
- College of Pharmacy, Chungnam National University RCTCP, Chungnam National University
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- Kim Young Ho
- College of Pharmacy, Chungnam National University
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Abstract
Nine compounds, including six phenylethanoid glycosides: acteoside (1); bioside (2); echinacoside (3); poliumoside (4); phenylethyl glycoside (5); salidroside (6) and three flavonoids; linarin (7); apigenin (8); isorhoifolin (9), were isolated from the flowers of Buddleja officinalis MAXIM. (Buddlejaceae). Chemical structures were confirmed by 1H-, and 13C-NMR, and MS spectral methods and compared with those reported in the literature. Antioxidant activities of the methanol and water extracts, and all isolated compounds were evaluated using the total oxidant scavenging capacity (TOSC) assay against peroxynitrite. Results of the assay showed that the phenylethanoid glycosides, a major class of compounds of the flowers of B. officinalis, possess strong antioxidant activity. Of these, acteoside, echinacoside and poliumoside have 9.9-, 9.8- and 9.5-fold TOSC value, respectively, compared with the positive control, Trolox.
Journal
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- Biological and Pharmaceutical Bulletin
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Biological and Pharmaceutical Bulletin 32 (12), 1952-1956, 2009
The Pharmaceutical Society of Japan
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Details 詳細情報について
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- CRID
- 1390282679605162240
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- NII Article ID
- 130000116977
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- NII Book ID
- AA10885497
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- ISSN
- 13475215
- 09186158
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- NDL BIB ID
- 10455593
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- Text Lang
- en
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- Data Source
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed