EFFECTS OF LOW INCIDENT ENERGY LEVELS OF INFRARED LASER IRRADIATON ON THE PROLIFERATION OF <i>CANDIDA ALBICANS</i>. PARTIII:

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  • Kim Ki-Suk
    <i>Department of Oral Medicine, College of Dentistry</i>
  • Kim Sam-Kum
    <i>Department of Oral Medicine, College of Dentistry</i>
  • Lee Phil-Yeon
    <i>Department of Oral Medicine, College of Dentistry</i>
  • Song Yun-Heon
    <i>Department of Oral Medicine, College of Dentistry</i>
  • Kim Ki-Beom
    <i>Department of Oral Medicine, College of Dentistry</i>
  • Jeon Eun-Hyoung
    <i>Department of Microbiology, College of Natural Sciences, Dankook Universty</i>
  • Ahn Tae-Young
    <i>Department of Microbiology, College of Natural Sciences, Dankook Universty</i>

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Other Title
  • A STUDY ON THE INTERIRRADIATION INTERVAL

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Description

This study was performed to investigate the biostimulation effects of low level laser therapy (LLLT) on the fungus, Candida albicans, according to the interval of irradiation during the cell cycle. Samples were randomly divided into 5 groups : pulse 7 with 2 hour interval (P7-2Hr), pulse 7 with 4 hour interval (p7-4Hr), pulse 15 with 2 hour interval (P15-2Hr), pulse 15 with 4 hour interval (P15-4Hr) and control (Co). Each of the experimental samples was irradiated for 1 minute with a 2 hour interval, or for 2 minutes with a 4 hour interval, during 28 hours of the cell cycle of C. albicans, and the optical density of the cultures as a marker of cell growth was assessed by spectrophotometry every 2 hours. It was found that there was a significant difference in cell growth between the 2 hour and 4 hour interval laser irradiation groups in favour of the 4 hour groups, although the total energy of both groups using an identical pulse setting was equal during the study. There was also a significant difference between the 4 hour interirradiation groups and the control group, but no significant difference between the 2 hour interirradiation groups and the control group. It is, therefore, concluded that frequent irradiation sessions using a short interirradiation interval with LLLT on cells do not induce any significant biostimulation effect on the cell growth at optimal dose or even at low doses of LLLT, and that an appropriate irradiation interval is required for the acceleration of cell growth.

Journal

  • LASER THERAPY

    LASER THERAPY 7 (4), 151-156, 1995

    International Phototherapy Association

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