THE DIRECT EFFECT OF 860 nm LIGHT ON CELL PROLIFERATION AND ON SUCCINIC DEHYDROGENASE ACTIVITY OF HUMAN FIBROBLASTS INVITRO

DOI 3 Citations 13 References
  • Bolton Peter
    <i>Tissue Repair Research Unit, Division of Anatomy and Cell Biology, United Medical and Dental Schools of Guy’s and St. Thomas’s Hospitals, Guy’s Hospital Campus</i>
  • Young Steve
    <i>Tissue Repair Research Unit, Division of Anatomy and Cell Biology, United Medical and Dental Schools of Guy’s and St. Thomas’s Hospitals, Guy’s Hospital Campus</i>
  • Dyson Mary
    <i>Tissue Repair Research Unit, Division of Anatomy and Cell Biology, United Medical and Dental Schools of Guy’s and St. Thomas’s Hospitals, Guy’s Hospital Campus</i>

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Description

Human forearm fibroblasts were irradiated, in vitro, using a Microlaser Medical Pen Unit (Johnson and Johnson) with a wavelength of 860 nm, and an average power output of 50 mW. The irradiation distance and times were adjusted to give energy densities of 2 J/cm2 and 16 J/cm2 respectively. The control unit was adjusted to give a continuous waveform. Fibroblast proliferation and succinic dehydrogenase activity were assessed every 24 hrs over a five day period. The results obtained suggest a relationship between fibroblast proliferation and succinic dehydrogenase activity. At the lower energy density (2 J/cm2), succinic dehydrogenase levels rise with fibroblast proliferation. However, at an energy density of 16 J/cm2, the succinic dehydrogenase levels and fibroblast proliferation appear to be inhibited. These findings agree with previously reported data.

Journal

  • LASER THERAPY

    LASER THERAPY 7 (2), 55-60, 1995

    International Phototherapy Association

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Details 詳細情報について

  • CRID
    1390282679608531840
  • NII Article ID
    130004872720
  • DOI
    10.5978/islsm.95-or-07
  • ISSN
    18847269
    08985901
  • Text Lang
    en
  • Data Source
    • JaLC
    • Crossref
    • CiNii Articles
  • Abstract License Flag
    Disallowed

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