Appetite-Enhancing Effects: The Influence of Concentrations of Benzylacetone and <i>trans</i>-Cinnamaldehyde and Their Inhalation Time, as Well as the Effect of Aroma, on Body Weight in Mice

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  • Ogawa Kakuyou
    Department of Pharmacognosy, Graduate School of Pharmaceutical Sciences, Kyoto University
  • Ito Michiho
    Department of Pharmacognosy, Graduate School of Pharmaceutical Sciences, Kyoto University

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  • Highlighted Paper selected by Editor-in-Chief : Appetite-Enhancing Effects : The Influence of Concentrations of Benzylacetone and trans-Cinnamaldehyde and Their Inhalation Time, as Well as the Effect of Aroma, on Body Weight in Mice

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Abstract

Benzylacetone has appetite-enhancing and locomotor-reducing effects. The effective doses for these two outcomes overlap, and the weight gain of mice exposed to benzylacetone is caused by both appetite-enhancement and a reduction in locomotor activity. The appetite-enhancing effects of trans-cinnamaldehyde and benzylacetone have been reported previously. In this study, these appetite-enhancing effects were seen in mice after short-term, high-dose exposure.

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