Study on Development of Polymeric Micellar Gene Carrier and Evaluation of Its Functionality
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- Oba Makoto
- Graduate School of Biomedical Sciences, Nagasaki University
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抄録
Polymeric micelles, which are formed by the self-assembly of block copolymers, can load various substances and have received attention as drug carriers. Negatively charged nucleic acids such as DNA or RNA are some of the drugs delivered by polyion complex-based polymeric micelles (polyplex micelles). Polyplex micelles are expected to be nonviral gene carriers instead of viral vectors, which have several problems including safety, the limited size of the loading gene, and productivity. In this review, recent studies by our group on smart polyplex micelles delivering genes will be introduced.
収録刊行物
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- Biological & Pharmaceutical Bulletin
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Biological & Pharmaceutical Bulletin 36 (7), 1045-1051, 2013
公益社団法人 日本薬学会
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詳細情報 詳細情報について
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- CRID
- 1390282679609272960
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- NII論文ID
- 130003361481
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- NII書誌ID
- AA10885497
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- COI
- 1:STN:280:DC%2BC3sjmsVKmsg%3D%3D
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- ISSN
- 13475215
- 09186158
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- HANDLE
- 10069/33641
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- NDL書誌ID
- 024644476
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- PubMed
- 23811553
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- IRDB
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可