Two cases of mucinous (non-cystic) carcinoma of the pancreas without intraductal papillary mucinous neoplasm

  • SAKODA Takuya
    Department of Surgery, Applied Life Sciences Institute of Biomedical & Health Sciences, Hiroshima University
  • MURAKAMI Yoshiaki
    Department of Surgery, Applied Life Sciences Institute of Biomedical & Health Sciences, Hiroshima University
  • UEMURA Kenichiro
    Department of Surgery, Applied Life Sciences Institute of Biomedical & Health Sciences, Hiroshima University
  • HASHIMOTO Yasushi
    Department of Surgery, Applied Life Sciences Institute of Biomedical & Health Sciences, Hiroshima University
  • KONDO Naru
    Department of Surgery, Applied Life Sciences Institute of Biomedical & Health Sciences, Hiroshima University
  • NAKAGAWA Naoya
    Department of Surgery, Applied Life Sciences Institute of Biomedical & Health Sciences, Hiroshima University
  • SASAKI Hayato
    Department of Surgery, Applied Life Sciences Institute of Biomedical & Health Sciences, Hiroshima University
  • SUEDA Taijiro
    Department of Surgery, Applied Life Sciences Institute of Biomedical & Health Sciences, Hiroshima University
  • SASAKI Tamito
    Department of Gastroenterology and Metabolism, Applied Life Sciences Institute of Biomedical & Health Sciences, Hiroshima University
  • SERIKAWA Masahiro
    Department of Gastroenterology and Metabolism, Applied Life Sciences Institute of Biomedical & Health Sciences, Hiroshima University
  • ISHII Yasutaka
    Department of Gastroenterology and Metabolism, Applied Life Sciences Institute of Biomedical & Health Sciences, Hiroshima University
  • ARIHIRO Koji
    Department of Anatomical Pathology, Hiroshima University
  • SHIROMA Noriyuki
    Department of Anatomical Pathology, Hiroshima University
  • HARATAKE Daisuke
    Department of Anatomical Pathology, Hiroshima University

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Other Title
  • 膵管内乳頭粘液性腫瘍を伴わない膵粘液癌の2切除例

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Description

We report two cases of mucinous (non-cystic) carcinoma of the pancreas. The first case was 73-year-old woman. Computed tomography showed a 45mm tumor in the pancreas head, and we performed pylorus-preserving pancreaticoduodenectomy. The pathological diagnosis was mucinous (non-cystic) carcinoma of the pancreas (T2N0M0 fStage II). The second case was 53-year-old man. Computed tomography showed a 47mm tumor in the pancreas tail, and we performed distal pancreatectomy. The tumor was diagnosed as mucinous (non-cystic) carcinoma of the pancreas (T2N0M0 fStage II). In the vast majority of cases, mucinous (non-cystic) carcinoma develops from pre-existing intraductal papillary mucinous neoplasms (IPMN). However, an IPMN component was not observed in the specimens from both cases. The pathological diagnosis was mucinous (non-cystic) carcinoma, a histological variant of invasive ductal carcinoma. Besides, the differential diagnosis of mucinous (non-cystic) carcinoma was difficult, since the endoscopic ultrasound-guided fine needle aspiration should not be indicated due to its cystic appearance. On the other hand, endoscopic ultrasonography showed characteristic images in both cases. Endoscopic ultrasonography may be useful in the differential diagnostics in patients with mucinous (non-cystic) carcinoma.

Journal

  • Suizo

    Suizo 30 (4), 600-606, 2015

    Japan Pancreas Society

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