Development of multicellular spheroid for cell-based therapy

DOI Web Site 2 Citations 40 References Open Access
  • Kusamori Kosuke
    Department of Biopharmaceutics and Drug Metabolism, Graduate School of Pharmaceutical Sciences, Kyoto University
  • Nishikawa Makiya
    Department of Biopharmaceutics and Drug Metabolism, Graduate School of Pharmaceutical Sciences, Kyoto University
  • Takahashi Yuki
    Department of Biopharmaceutics and Drug Metabolism, Graduate School of Pharmaceutical Sciences, Kyoto University
  • Takakura Yoshinobu
    Department of Biopharmaceutics and Drug Metabolism, Graduate School of Pharmaceutical Sciences, Kyoto University

Bibliographic Information

Other Title
  • 細胞スフェロイド化技術の開発と細胞治療への応用
  • サイボウ スフェロイドカ ギジュツ ノ カイハツ ト サイボウ チリョウ エ ノ オウヨウ

Search this article

Description

Recent great advances in the preparation and culture of cells have expanded the expectation of therapeutic treatment using cells as "drugs". Cells play pivotal roles in biological processes through the interaction with surrounding cells and extracellular matrix. Therefore, multicellular spheroids, which can be obtained by culturing cells in three-dimension, have attracted great attention as an administration form that maximizes the function of cells. Here we summarize and compare several approaches to preparing multicellular spheroids and introduce our recent efforts on this subject.

Journal

  • Drug Delivery System

    Drug Delivery System 28 (1), 45-53, 2013

    THE JAPAN SOCIETY OF DRUG DELIVERY SYSTEM

Citations (2)*help

See more

References(40)*help

See more

Related Projects

See more

Keywords

Details 詳細情報について

Report a problem

Back to top